Chemodiversity of Ladder-Frame Prymnesin Polyethers in Prymnesium parvum
نویسندگان
چکیده
منابع مشابه
Chemodiversity of Ladder-Frame Prymnesin Polyethers in Prymnesium parvum.
Blooms of the microalga Prymnesium parvum cause devastating fish kills worldwide, which are suspected to be caused by the supersized ladder-frame polyether toxins prymnesin-1 and -2. These toxins have, however, only been detected from P. parvum in rare cases since they were originally described two decades ago. Here, we report the isolation and characterization of a novel B-type prymnesin, base...
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The cytotoxic events leading to lysis induced in Ehrlich ascites tumor (E.A.) cells by Prymnesium parvum cell extracts were followed microscopically and measured quantitatively as changes in E.A. cell volume, uptake of trypan blue, and release of macromolecular constituents from the cells. Cell swelling was the most immediate response to P. parvum cytotoxin, while cell death and lysis were late...
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Many microbes cooperatively secrete extracellular products that favorably modify their environment. Consistent with social evolution theory, structured habitats play a role in maintaining these traits in microbial model systems, by localizing the benefits and separating strains that invest in these products from 'cheater' strains that benefit without paying the cost. It is thus surprising that ...
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Toxin production is widespread among aquatic microalgae, suggesting a functional advantage for organisms producing toxic compounds. However, the biological role of algal toxin production is only vaguely understood. Here, we show that excretion of a toxic substance in the phagotrophic phytoflagellate Prymnesium parvum (Prymnesiophyceae) constitutes a mechanism to immobilize and seize motile prey...
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ژورنال
عنوان ژورنال: Journal of Natural Products
سال: 2016
ISSN: 0163-3864,1520-6025
DOI: 10.1021/acs.jnatprod.6b00345